Xapuri is a municipality located in the southeast of the Brazilian state of Acre. It was the scene of an early bloodless victory during the war to make Acre independent of Bolivia. The town is known as the birthplace of the rubber tapper and environmentalist Chico Mendes and of the surgeon and professor Adib Jatene.
Xapuri is at the point where the Xapuri River meets the Acre River. Its name is said to come from the Indigenous word Chapury, meaning "river meeting". Another explanation is that its name comes from the indigenous tribe of "Xapury" people. The town is about 12 km northwest of the BR-317 highway which leads from Rio Branco, 241 km to the east, to Brasiléia, 74 km to the west. It has broad streets and wooden houses. The area of the municipality is 5347.468 km2. It is 12th largest in area in Acre. It is bounded by the municipality of Sena Madureira to the west, Rio Branco to the north, Capixaba to the east, Epitaciolândia to the south, and Brasiléia to the southwest.
The municipality contains part of the 931537 ha Chico Mendes Extractive Reserve, a sustainable use environmental unit created in 1990. The reserve is fairly well maintained apart from a few locations of deforestation, but its surroundings are quite deforested, compromising its buffer zone.
